Osteoadherin is a recently described bone proteoglycan containing keratan sulfate. It promotes integrin (αvβ3)-mediated cell binding (Wendel, M., Sommarin, Y., and Heinegård, D. (1998) J. Cell Biol. 141, 839–847). The primary structure of bovine osteoadherin has now been determined by nucleotide sequencing of a cDNA clone from a primary bovine osteoblast expression library. The entire
Cellular and biomolecular interactions of osteoadherin with neurotrophic factors. Structural and functional studies on the streptococcal adhesion agI/II.
This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it. This page was last edited on 12 A small cell-binding proteoglycan for which we propose the name osteoadherin was extracted from bovine bone with guanidine hydrochloride–containing EDTA. It was purified to homogeneity using a combination of ion-exchange chromatography, hydroxyapatite chromatography, and gel filtration. The Mr of the proteoglycan was 85,000 as determined by Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP).
Each structure has advantages, and if used correctly and in the right environment, the structure can further the comple Organizational structure provides the guidelines for the system of reporting that drives an organization, dividing it into areas or departments that are responsible for certain aspects of the organization's purpose; it shows the relationshi Naturally occurring structures include canyons such as the Grand Canyon in the United States, mountains such as Mount Everest, and even homes and nests tha Naturally occurring structures include canyons such as the Grand Canyon in the Unite What is structuralism? Learn more about the school of thought and examples of it in various fields. Examples of structuralism differ based on the field they are associated with. Structuralism is a school of thought in linguistics, psycholog There are a number ways you can structure your company management. However, the best organizational structure is one that fits your management style, company size and overall marketing strategy.
Signal Transduction Cytoskeleton / ECM Extracellular Matrix Structures Bone Osteoadherin antibody; Osteoadherin proteoglycan antibody; Osteomodulin
Structure. Like other glycosaminoglycans keratan sulfate is a linear polymer that consists of a repeating disaccharide unit. Keratan sulfate occurs as a proteoglycan (PG) in which KS chains are attached to cell-surface or extracellular matrix proteins, termed core proteins.
Three primary structures have become the foundation for how an organization is run: functional; projectized; and matrix. Each structure has advantages, and if used correctly and in the right environment, the structure can further the comple
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The primary structure of bovine osteoadherin has now been determined by nucleotide sequencing of a cDNA clone from a primary
1998-07-03 · In order to further characterize osteoadherin, we have determined its primary structure. This reveals that osteoadherin belongs to the LRR family of connective tissue proteins. Osteoadherin is primarily expressed by mature osteoblasts, as shown in studies of its expression by in situ hybridization.
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Here we used immunohistochemistry to investigate the distribution of class I (biglycan, decorin, asporin, ECM2 and ECMX) and class II (fibromodulin, lumican, prolargin, keratocan and osteoadherin) small leucine-rich proteoglycans in human cutaneous Pacinian corpuscles. Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucinerich proteoglycans (SLRP). LRR motifs consist of approximately 2030 amino acids (aa) with conserved leucine spacing, folded into a structure with one βsheet and one The primary structure of bovine osteoadherin has now been determined by nucleotide sequencing of a cDNA clone from a primary bovine osteoblast expression library.
The entire
Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs.
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Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP). LRR motifs consist of approximately 20‑30 amino acids (aa) with conserved leucine spacing, folded into a structure with one beta -sheet and one alpha -helix (1, 2).
KS chains in fibromodulin and osteoadherin are relatively short (8–9 disaccharides) and are more highly sulfated than KS in cornea (Lauder et al., 1997). KS in fibromodulin lacks the clear domain structure of corneal KS, but like corneal KS it displays reduced Gal sulfation near the reducing terminus. The LRR‐containing proteins include a family of nine small proteoglycans, forming three distinct subfamilies: class I contains biglycan/PG‐I and decorin/PG‐II; class II: lumican, fibromodulin, PRELP, keratocan, and osteoadherin; and class III: epiphycan/PG‐Lb and osteoglycin or osteoinductive factor.
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Osteoadherin. Short name: OSAD 3D structure databases. SMR i: Q9Z1S7: ModBase i: Search Family & Domains i Domains and Repeats. Feature key Position(s) Description Actions Graphical view Length; Domain i: 53 – 91: LRRNT Add
Structuralism is a school of thought in linguistics, psychology and anthropology. It is also used as a method of criticizing works of literature. According to Pur Frank Lloyd Wright was one of the main players who helped shape Chicago's architectural aesthetic. His houses, museums and chapels are scattered all over the country. Some of his buildings are obviously his design, but there are some others There are many ways to structure a business. Five of the more basic types include sole proprietorship, general partnership, limited partnership, limited liability partnership and a corporation.